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Tao Liu’s indexed work centers on the development and application of mass spectrometry-based methods for deep proteomic profiling. Early first-author research established foundational protocols for human plasma n-glycoproteome analysis using immunoaffinity subtraction and hydrazide chemistry, a method that has garnered over 400 citations for its role in biomarker discovery. This technical focus evolved into high-throughput strategies, including quantitative cysteinyl-peptide enrichment technology and more recent senior-authored advancements in single-cell analysis. Publicly indexed outputs suggest a significant shift toward clinical applications, exemplified by his work on altered O-GlcNAcylation in Alzheimer’s disease proteins and the use of isobaric labeling to amplify signals in precise quantitative single-cell proteomics. Beyond lead-author methodological papers, Liu has contributed to major international consortia efforts that integrate proteomics with genomics to map the molecular landscapes of various malignancies. He served as a co-author on high-impact studies involving the proteogenomic characterization of human colon, breast, and lung cancers, which have collectively defined new therapeutic vulnerabilities in oncology. His portfolio also includes a highly cited reproducible workflow for multiplexed phosphoproteome analysis of tumor tissues published in Nature Protocols. These contributions reflect a career arc dedicated to refining the sensitivity of mass spectrometry to better understand complex biological systems and disease progression through large-scale molecular data.
Philipp Mertins, D R Mani, Kelly V Ruggles, Michael A Gillette, Karl R Clauser, Pei Wang, Xianlong Wang, Jana W Qiao, Song Cao, Francesca Petralia, Emily Kawaler, Filip Mundt, Karsten Krug, Zhidong Tu, Jonathan T Lei, Michael L Gatza, Matthew Wilkerson, Charles M Perou, Venkata Yellapantula, Kuan-lin Huang, Chenwei Lin, Michael D McLellan, Ping Yan, Sherri R Davies, R Reid Townsend, Steven J Skates, Jing Wang, Bing Zhang, Christopher R Kinsinger, Mehdi Mesri, Henry Rodriguez, Li Ding, Amanda G Paulovich, David Fenyö
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Bing Zhang, Jing Wang, Xiaojing Wang, Jing Zhu, Qi Liu, Zhiao Shi, Matthew C Chambers, Lisa J Zimmerman, Kent F Shaddox, Sangtae Kim, Sherri R Davies, Sean Wang, Pei Wang, Christopher R Kinsinger, Robert C Rivers, Henry Rodriguez, R Reid Townsend, Matthew J C Ellis, Steven A Carr, David L Tabb, Robert J Coffey, Robbert J C Slebos, Daniel C Liebler, NCI CPTAC
Suhas Vasaikar, Chen Huang, Xiaojing Wang, Vladislav A Petyuk, Sara R Savage, Bo Wen, Yongchao Dou, Yun Zhang, Zhiao Shi, Osama A Arshad, Marina A Gritsenko, Lisa J Zimmerman, Jason E McDermott, Therese R Clauss, Ronald J Moore, Rui Zhao, Matthew E Monroe, Yi-Ting Wang, Matthew C Chambers, Robbert J C Slebos, Ken S Lau, Qianxing Mo, Li Ding, Matthew Ellis, Mathangi Thiagarajan, Christopher R Kinsinger, Henry Rodriguez, Richard D Smith, Karin D Rodland, Daniel C Liebler, Tao Liu, Bing Zhang, Clinical Proteomic Tumor Analysis Consortium
Liang-Bo Wang, Alla Karpova, Marina A Gritsenko, Jennifer E Kyle, Song Cao, Yize Li, Dmitry Rykunov, Antonio Colaprico, Joseph H Rothstein, Runyu Hong, Vasileios Stathias, MacIntosh Cornwell, Francesca Petralia, Yige Wu, Boris Reva, Karsten Krug, Pietro Pugliese, Emily Kawaler, Lindsey K Olsen, Wen-Wei Liang, Xiaoyu Song, Yongchao Dou, Michael C Wendl, Wagma Caravan, Wenke Liu, Daniel Cui Zhou, Jiayi Ji, Chia-Feng Tsai, Vladislav A Petyuk, Jamie Moon, Weiping Ma, Rosalie K Chu, Karl K Weitz, Ronald J Moore, Matthew E Monroe, Rui Zhao, Xiaolu Yang, Seungyeul Yoo, Azra Krek, Alexis Demopoulos, Houxiang Zhu, Matthew A Wyczalkowski, Joshua F McMichael, Brittany L Henderson, Caleb M Lindgren, Hannah Boekweg, Shuangjia Lu, Jessika Baral, Lijun Yao, Kelly G Stratton, Lisa M Bramer, Erika Zink, Sneha P Couvillion, Kent J Bloodsworth, Shankha Satpathy, Weiva Sieh, Simina M Boca, Stephan Schürer, Feng Chen, Maciej Wiznerowicz, Karen A Ketchum, Emily S Boja, Christopher R Kinsinger, Ana I Robles, Tara Hiltke, Mathangi Thiagarajan, Alexey I Nesvizhskii, Bing Zhang, D R Mani, Michele Ceccarelli, Xi S Chen, Sandra L Cottingham, Qing Kay Li, Albert H Kim, David Fenyö, Kelly V Ruggles, Henry Rodriguez, Mehdi Mesri, Samuel H Payne, Adam C Resnick, Pei Wang, Richard D Smith, Antonio Iavarone, Milan G Chheda, Jill S Barnholtz-Sloan, Karin D Rodland, Tao Liu, Li Ding, Clinical Proteomic Tumor Analysis Consortium
Michael A Gillette, Shankha Satpathy, Song Cao, Saravana M Dhanasekaran, Suhas V Vasaikar, Karsten Krug, Francesca Petralia, Yize Li, Wen-Wei Liang, Boris Reva, Azra Krek, Jiayi Ji, Xiaoyu Song, Wenke Liu, Runyu Hong, Lijun Yao, Lili Blumenberg, Sara R Savage, Michael C Wendl, Bo Wen, Kai Li, Lauren C Tang, Melanie A MacMullan, Shayan C Avanessian, M Harry Kane, Chelsea J Newton, MacIntosh Cornwell, Ramani B Kothadia, Weiping Ma, Seungyeul Yoo, Rahul Mannan, Pankaj Vats, Chandan Kumar-Sinha, Emily A Kawaler, Tatiana Omelchenko, Antonio Colaprico, Yifat Geffen, Yosef E Maruvka, Felipe da Veiga Leprevost, Maciej Wiznerowicz, Zeynep H Gümüş, Rajwanth R Veluswamy, Galen Hostetter, David I Heiman, Matthew A Wyczalkowski, Tara Hiltke, Mehdi Mesri, Christopher R Kinsinger, Emily S Boja, Gilbert S Omenn, Arul M Chinnaiyan, Henry Rodriguez, Qing Kay Li, Scott D Jewell, Mathangi Thiagarajan, Gad Getz, Bing Zhang, David Fenyö, Kelly V Ruggles, Marcin P Cieslik, Ana I Robles, Karl R Clauser, Ramaswamy Govindan, Pei Wang, Alexey I Nesvizhskii, Li Ding, D R Mani, Steven A Carr, Clinical Proteomic Tumor Analysis Consortium