Bernd Bodenmiller

Bernd Bodenmiller | JRNLClub

Research Statement

AI generated · 6d ago

Bernd Bodenmiller's research centers on highly multiplexed tissue imaging and single-cell proteomics, particularly how tumor and immune ecosystems organize at subcellular resolution. His most-cited indexed work includes mass-cytometry imaging of tumor tissues at subcellular resolution, which established a widely used platform for mapping dozens of markers simultaneously, and an immune atlas of clear cell renal cell carcinoma, a large-scale dissection of immune populations within tumors. He has also applied these approaches to the single-cell pathology landscape of breast cancer, linking spatially resolved tumor and immune features to disease structure, and to cancer-associated fibroblast classification across single-cell and spatial proteomics data. Beyond these, Bodenmiller contributed as a middle author to consortium efforts including the Human Cell Atlas and the NIH Human Biomolecular Atlas Program, helping shape reference maps of human cell types. Earlier work spans reproducible isolation of overlapping phosphoproteome segments and mass-tag cell barcoding with doublet filtering, methodological foundations for his later imaging work. No software, datasets, grants, or patents are indexed beyond publications. Across these outputs, his trajectory runs from proteomic method development toward spatially resolved, single-cell atlases of tumor immunity.

Most Cited Works

The Human Cell Atlas

Aviv Regev, Sarah A Teichmann, Eric S Lander, Ido Amit, Christophe Benoist, Ewan Birney, Bernd Bodenmiller, Peter Campbell, Piero Carninci, Menna Clatworthy, Hans Clevers, Bart Deplancke, Ian Dunham, James Eberwine, Roland Eils, Wolfgang Enard, Andrew Farmer, Lars Fugger, Berthold Göttgens, Nir Hacohen, Muzlifah Haniffa, Martin Hemberg, Seung Kim, Paul Klenerman, Arnold Kriegstein, Ed Lein, Sten Linnarsson, Emma Lundberg, Joakim Lundeberg, Partha Majumder, John C Marioni, Miriam Merad, Musa Mhlanga, Martijn Nawijn,

Research Areas

Single-cell and spatial transcriptomicsCancer Immunotherapy and BiomarkersCell Image Analysis TechniquesAdvanced Proteomics Techniques and AppliGlioma Diagnosis and Treatment

Loading ORCID activity...

Bernd Bodenmiller

Sources

Research Statement

Most Cited Works

The Human Cell Atlas

Research Areas

Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry

An Immune Atlas of Clear Cell Renal Cell Carcinoma

The single-cell pathology landscape of breast cancer

A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer