Andrew Francis Hill

Andrew Francis Hill | JRNLClub

Research Statement

AI generated · Oct 25, 2026

Andrew Francis Hill's most-cited work centres on prion strain typing and the link between bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease, established through his senior-authored 1996 Nature analysis and his first-authored 1997 follow-up showing the same strain causes both disorders. He extended this line into diagnostics with tonsil biopsy for detecting human prion disease, work that helped define tissue-based approaches to vCJD surveillance. More recently his indexed output has shifted toward extracellular vesicles, including a widely cited worldwide survey of isolation and characterization techniques for extracellular vesicles and studies of exosomal miRNA as a protective, enriched source for biomarker profiling. Beyond these, Hill contributed as a middle author to the community's MISEV reporting frameworks for extracellular vesicle studies, including the 2018 and 2023 position statements, and to Vesiclepedia, a continuously annotated compendium of vesicle data. He also co-authored FunRich, an open-access functional enrichment and interaction network tool. Clotilde Théry appears among his indexed collaborators on this vesicle-focused work. Across the portfolio, the throughline runs from misfolded-protein transmission in prion disease to the vesicle and small-RNA biology that now underpins his biomarker research.

Most Cited Works

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Clotilde Théry, Kenneth W Witwer, Elena Aikawa, Maria Jose Alcaraz, Johnathon D Anderson, Ramaroson Andriantsitohaina, Anna Antoniou, Tanina Arab, Fabienne Archer, Georgia K Atkin-Smith, D Craig Ayre, Jean-Marie Bach, Daniel Bachurski, Hossein Baharvand, Leonora Balaj, Shawn Baldacchino, Natalie N Bauer, Amy A Baxter, Mary Bebawy, Carla Beckham, Apolonija Bedina Zavec, Abderrahim Benmoussa, Anna C Berardi, Paolo Bergese, Ewa Bielska, Cherie Blenkiron, Sylwia Bobis-Wozowicz, Eric Boilard, Wilfrid Boireau, Antonella Bongiovanni, Francesc E Borràs

Research Areas

Alzheimer's disease research and treatmeExtracellular vesicles in diseasePrion Diseases and Protein MisfoldingAmyloidosis: Diagnosis, Treatment, OutcoCellular transport and secretion

Affiliations & Education

Education

1993–1998
Imperial College Faculty of Medicine(GB)
DIC · Biochemistry
Victoria University of Wellington(NZ)
BSc(HONS) · School of Biological Sciences
1988–1990
Victoria University of Wellington(NZ)
BSc · School of Biological Sciences

Employment

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Andrew Francis Hill

Sources

Research Statement

Most Cited Works

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Research Areas

Affiliations & Education

Education

Employment

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD

Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper