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Aleksandra Deczkowska’s indexed work centers on the role of microglia and immune signaling in neurodegeneration and brain aging. Her most-cited first-author paper, a 2018 *Cell* review, established disease-associated microglia as a universal immune sensor of neurodegeneration, accumulating over 1,500 citations. She further defined the field with a 2020 *Cell* review on the physiology, pathology, and therapeutic potential of the TREM2 signaling pathway, and experimentally demonstrated that Mef2C restrains microglial inflammatory responses in a 2017 *Nature Communications* study, linking its loss to brain aging. These contributions collectively frame microglial immune checkpoints as central to neurological disease. Beyond her lead-author reviews, Deczkowska contributed to several high-impact collaborative studies. She was a middle author on a 2019 *Cell* paper describing lipid-associated macrophages that control metabolic homeostasis in a Trem2-dependent manner, and on a 2021 *Nature* study showing that NASH limits anti-tumour surveillance in immunotherapy-treated HCC. Her earlier work includes contributions to a 2016 *Science* paper on microglia development following a stepwise program to regulate brain homeostasis. Across these publications, her research consistently explores how immune cells—both in the brain and periphery—sense and respond to tissue stress, with implications for neurodegeneration, metabolic disease, and cancer immunotherapy.
Aleksandra Deczkowska, Hadas Keren-Shaul, Assaf Weiner, Marco Colonna, Michal Schwartz, Ido Amit
Diego Adhemar Jaitin, Lorenz Adlung, Christoph A Thaiss, Assaf Weiner, Baoguo Li, Hélène Descamps, Patrick Lundgren, Camille Bleriot, Zhaoyuan Liu, Aleksandra Deczkowska
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Dominik Pfister, Nicolás Gonzalo Núñez, Roser Pinyol, Olivier Govaere, Matthias Pinter, Marta Szydlowska, Revant Gupta, Mengjie Qiu, Aleksandra Deczkowska, Assaf Weiner, Florian Müller, Ankit Sinha, Ekaterina Friebel, Thomas Engleitner, Daniela Lenggenhager, Anja Moncsek, Danijela Heide, Kristin Stirm, Jan Kosla, Eleni Kotsiliti, Valentina Leone, Michael Dudek, Suhail Yousuf, Donato Inverso, Indrabahadur Singh, Ana Teijeiro, Florian Castet, Carla Montironi, Philipp K Haber, Dina Tiniakos, Pierre Bedossa, Simon Cockell, Ramy Younes, Michele Vacca, Fabio Marra, Jörn M Schattenberg, Michael Allison, Elisabetta Bugianesi, Vlad Ratziu, Tiziana Pressiani, Antonio D'Alessio, Nicola Personeni, Lorenza Rimassa, Ann K Daly, Bernhard Scheiner, Katharina Pomej, Martha M Kirstein, Arndt Vogel, Markus Peck-Radosavljevic, Florian Hucke, Fabian Finkelmeier, Oliver Waidmann, Jörg Trojan, Kornelius Schulze, Henning Wege, Sandra Koch, Arndt Weinmann, Marco Bueter, Fabian Rössler, Alexander Siebenhüner, Sara De Dosso, Jan-Philipp Mallm, Viktor Umansky, Manfred Jugold, Tom Luedde, Andrea Schietinger, Peter Schirmacher, Brinda Emu, Hellmut G Augustin, Adrian Billeter, Beat Müller-Stich, Hiroto Kikuchi, Dan G Duda, Fabian Kütting, Dirk-Thomas Waldschmidt, Matthias Philip Ebert, Nuh Rahbari, Henrik E Mei, Axel Ronald Schulz, Marc Ringelhan, Nisar Malek, Stephan Spahn, Michael Bitzer, Marina Ruiz de Galarreta, Amaia Lujambio, Jean-Francois Dufour, Thomas U Marron, Ahmed Kaseb, Masatoshi Kudo, Yi-Hsiang Huang, Nabil Djouder, Katharina Wolter, Lars Zender, Parice N Marche, Thomas Decaens, David J Pinato, Roland Rad, Joachim C Mertens, Achim Weber, Kristian Unger, Felix Meissner, Susanne Roth, Zuzana Macek Jilkova, Manfred Claassen, Quentin M Anstee, Ido Amit, Percy Knolle, Burkhard Becher, Josep M Llovet, Mathias Heikenwalder
Orit Matcovitch-Natan, Deborah R Winter, Amir Giladi, Stephanie Vargas Aguilar, Amit Spinrad, Sandrine Sarrazin, Hila Ben-Yehuda, Eyal David, Fabiola Zelada González, Pierre Perrin, Hadas Keren-Shaul, Meital Gury, David Lara-Astaiso, Christoph A Thaiss, Merav Cohen, Keren Bahar Halpern, Kuti Baruch, Aleksandra Deczkowska, Erika Lorenzo-Vivas, Shalev Itzkovitz, Eran Elinav, Michael H Sieweke, Michal Schwartz, Ido Amit
Aleksandra Deczkowska, Assaf Weiner, Ido Amit